What Does “Praying in the Holy Spirit” Mean?

But you, dear friends, by building yourselves up in your most holy faith and praying in the Holy Spirit,
Jude 1:20 NIV

Dear friends, use your most holy faith to grow. Pray with the Holy Spirit’s help.
Jude 1:20 GW

Almost all translations render it, “in the [power of the–GNT, NLT] Holy Spirit”.

Praying in the Holy Ghost. Observe, [1.] Prayer is the nurse of faith; the way to build up ourselves in our most holy faith is to continue instant in prayer, Rom 12:12. [2.] Our prayers are then most likely to prevail when we pray in the Holy Ghost, that is, under his guidance and influence, according to the rule of his word, with faith, fervency, and constant persevering [Luke 11:5-10, Luke 18:1-8]; this is praying in the Holy Ghost, whether it be done by or without a set prescribed form.

–Matthew Henry

For those who live according to the flesh set their minds on the things of the flesh, but those who live according to the Spirit set their minds on the things of the Spirit. For to set the mind on the flesh is death, but to set the mind on the Spirit is life and peace.
Romans 8:5-6 ESV

If you believe, you will receive whatever you ask for in prayer.”
Matthew 21:22 NIV

Do not be slothful in zeal, be fervent in spirit, serve the Lord.
Romans 12:12 GW

This is the confidence we have in approaching God: that if we ask anything according to his will, he hears us.
1 John 5:14 NIV

Also see:
God’s Will For You | Scripture Zealot blog

persistence

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