God is a personal God who responds. That is one of the great lessons of the psalms; it is one of the grand assumptions of the prayers of Paul.

…

“The degree of our peace of mind is tied to our prayer life (Philippians 4:6-7). This is not because prayer is psychologically soothing, but because we address a prayer-answering God, a personal God, a responding God, a sovereign God whom we can trust with the outcomes of life’s conclusions. And we learn, with time, that if God in this or that instance does not choose to take away the suffering, or utterly remove the evil, he does send grace and power. The result is praise; and that, of course, is itself enjoyable, in exactly the same way that lovers enjoy giving each other compliments.

–D.A. Carson, How Long O Lord?

Psalm 73:26 HCSB
My flesh and my heart may fail, but God is the strength of my heart, my portion forever.

Psalm 119:28
I am weary from grief; strengthen me through Your word.

2 Corinthians 12:7-9
so that I would not exalt myself, a thorn in the flesh was given to me, a messsenger of Satan to torment me so I would not exalt myself. 8 Concerning this, I pleaded with the Lord three times to take it away from me. 9 But He said to me, “My grace is sufficient for you, for power is perfected in weakness.” Therefore, I will most gladly boast all the more about my weaknesses, so that Christ’s power may reside in me.